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Nogusa S, Thapa RJ, Dillon CP, Liedmann S, Oguin 3rdTH, Ingram JP, Rodriguez DA, Kosoff R, Sharma S, Sturm O et al..  2016.  RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.. Cell Host Microbe. 20(1):13-24.
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Latest News

  • ImmuNet
    A network model of protein-protein interactions in human dendritic cells using a Bayesian integration framework. The network integrates PRIME-generated data with other publicly available datasets.
    ImmuNet
  • PRiME is pleased to announce that we have been awarded by NIAID U19 grant through April 2020 to advance our experiment based modeling of the immune response to Influenza infection.

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Recent Publications

  • Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses
  • Comparative analysis of anti-viral transcriptomics reveals novel effects of influenza immune antagonism.
  • Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases
  • Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death.
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