CoRegulation Explorer

Coregulation Explorer (CorEx), a web-based tool for coregulation analysis

This interactive correlation mapping tool allows to combine correlations maps based on multidimensional scaling (MDS) analysis and hierarchical clustering, with Transcription Factor (TF) enrichment analysis. Experimental data are uploaded via the web interface, and CorEx performs an MDS analysis and provides the hierarchical clustering and correlation matrices. The user can then select clusters of interest for TF enrichment analysis. The application will identify TFs whose binding sites are significantly enriched within the promoters of the genes forming those clusters.