Modeling of the immune response of interferon-β pretreated human DCs to influenza virus infection

Pretreatment of human DCs with interferon-β enhances their immune response to influenza virus infection. The expression levels of several key players of the immune response were measured over a period of 13 hours, during pretreatment and after viral infection. Based on those measurements, a comprehensive computational model was developed, providing insights into the effects of duration and strength of interferon pretreatment.
A complete description of the model as well as an interactive web interface are available.