Transcriptional-Pulsing Model

The model consists of the master equation for a transcriptional pulsing model of mRNA distributions, which allows to investigate how the time constants associated with episodes of transcriptional bursting and mRNA and protein degradation rates lead to different cellular mRNA and protein distributions. The model finds that, among others, bimodal and long-tailed power-law distributions occur in the steady state as the rate constants are varied over biologically significant time scales.
( Stochasticity of gene products from transcriptional pulsing, Iyer-Biswas, Srividya, Hayot Fernand, and Jayaprakash Ciriyam , Phys Rev E 79(3), (2009)).